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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: J Tissue Eng Regen Med. 2011 Jun 28;6(5):369–377. doi: 10.1002/term.439

Figure 5. BMSC bioreactor effluents have enhanced anti-inflammatory properties.

Figure 5

Upregulation of IL-10 in peripheral blood mononuclear cells (PBMCs) after exposure to unconcentrated medium harvested from BMSCs cultured in 2D flasks or 3D bioreactors. PBMCs were incubated in the medium for 18 hours, after which, cells were stimulate with LPS for 5 hours. Supernatant was collected and measured for IL-10 through ELISA; *p < 0.05, **p < 0.001. Baseline results represent PBMCs incubated with unconditioned medium. N=3.