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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Pharmacol Biochem Behav. 2011 Jul 7;100(1):17–24. doi: 10.1016/j.pbb.2011.07.001

Figure 1.

Figure 1

Conditioning and test amplitudes (left) and T/C ratios (right) before and after varenicline administration at four different doses. Varenicline injection (IP) occurred at the dotted line. Records were obtained at 5 minute intervals following injection. Varenicline produced improvements in P20-N40 inhibition at each dose tested as indicated by the significant decreases in T/C ratios (left) as compared to baseline values. Asterisks indicate time points following varenicline administration where a significant effect, as determined by Fisher’s PLSD, on either the conditioning amplitude (upper asterisks) or test amplitude (lower asterisks) were found as compared to an averaged baseline for the corresponding dose. Data are mean ± SEM. *p<0.05, **p<0.01