Figure 3.
Inhibition of varenicline (0.6 mg/kg, IP) induced improvement of P20-N40 inhibition by BTX (1 μl of 1.25 nM, ICV). The first five time points (baseline) refer to baseline recordings obtained prior to varenicline injection (0.6 mg/kg, IP). Injection of the α7 antagonist BTX (dotted line) occurred 20 minutes prior to injection of varenicline (dashed line). (●) Represent conditioning amplitude values and (Δ) represent the test amplitude values at each time point. Data are mean ± SEM; n = 8.