Table 1.
MALES | Maternal Diet | ||
---|---|---|---|
Postweaning diet | Control | Low Protein | |
Fasting glucose | Control | 102.3 (15.8) | 162.0 (14.8)* |
High fat | 199.7 (26.3)† | 178.5 (17.3) | |
AUC-IPGTT | Control | 874.2 (88) | 810.7 (32) |
High fat | 988.4 (88) | 1038.2 (78.5) | |
FEMALES | Maternal Diet | ||
Postweaning diet | Control | Low Protein | |
Fasting glucose | Control | 154.4 (6.6) | 150.2 (5.5) |
High fat | 176 (5.2)† | 186.4 (13.8)† | |
AUC-IPGTT | Control | 593.2 (29.8) | 636.3 (23.5) |
High fat | 725.7 (62.6) | 682.7 (22.9) |
Glucose tolerance test performed after 18hr fast. Male mice from LP pregnancies demonstrate a significantly elevated fasting glucose level when maintained on the control diet from weaning compared to mice from control pregnancies (* p<.05, mean ± S.E.M.).
Animals weaned to the high fat diet had significantly increased fasting glucose levels as compared to animals on the control diet in the glucose tolerance test, as indicated (†p<.05, mean ± S.E.M.).