Table 2.
Number of animals achieving bony bridging or exhibiting cortical bone resorption after 5 weeks of healing for each region of the callus
| Region | S group | F group | D1 group | D3 group | D4 group |
|---|---|---|---|---|---|
| Periosteal callus bridging | |||||
| Medial | 3/8 | 2/8 | 3/8 | 9/9 | 8/8 |
| Lateral | 3/8 | 0/8 | 1/8 | 7/9 | 6/8 |
| Intracortical callus bridging | |||||
| Medial | 4/8 | 3/8 | 1/8 | 7/9 | 8/8 |
| Lateral | 1/8 | 2/8 | 1/8 | 6/9 | 8/8 |
| Total % bridging (periosteal + intracortical), bridging score* | 34%, 1.4 ± 1.4 | 22%, 0.9 ± 1.0 | 19%, 0.8 ± 1.4 | 81%, 3.2 ± 1.2 | 94%, 3.8 ± 0.5 |
| Endosteal callus bridging | 5/8 | 3/8 | 1/8 | 2/9 | 3/8 |
| Cortical bone resorption | |||||
| Distal medial | 2/8 | 3/8 | 5/8 | 2/9 | 3/8 |
| Distal lateral | 5/8 | 6/8 | 7/8 | 3/9 | 5/8 |
| Proximal medial | 8/8 | 7/8 | 8/8 | 2/9 | 4/8 |
| Proximal lateral | 4/8 | 7/8 | 8/8 | 2/9 | 2/8 |
| Total % resorption (distal + proximal) | 59% | 72% | 88% | 25% | 44% |
* Values are expressed as mean ± SD; S group = continuously stiff fixation; F group = continuously flexible fixation; D1 group = dynamization at 1 week; D3 group = dynamization at 3 weeks; D4 group = dynamization at 4 weeks.