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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Stroke. 2011 Sep 1;42(10):2990–2994. doi: 10.1161/STROKEAHA.111.620765

Figure 1.

Figure 1

Distribution of MTD selection by the CRM and even randomization. The true MTD is dose tier 3 (which has 10% DLT). Logistic regression is used to make dose selection at the end of each simulated trial.