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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Clin Immunol. 2011 Jul 2;141(1):103–110. doi: 10.1016/j.clim.2011.06.005

Figure 2. Level and frequency of antibody reactivity to differentially targeted peptides of VlsE, as determined by peptide microarray epitope mapping.

Figure 2

A) Mean level of antibody reactivity to each of the 14 peptides in PLDS (n=13), post-Lyme healthy (n=9), and non-Lyme healthy (n=16) groups. Error bars represent the standard error of the mean. Among these 14 peptides, reactivity towards 5 peptides, forming 3 contiguous amino acid sequences, was significantly higher in the PLDS group than in the post-Lyme healthy group. These peptides are shown by asterisks (1 asterisk indicates p<0.05, while 2 asterisks indicates p< 0.01 for the comparison between PLDS and post-Lyme healthy groups. B) Frequency of positivity for IgG antibodies to each of the 14 peptides in the PLDS, post-Lyme healthy, and non-Lyme healthy groups.