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. Author manuscript; available in PMC: 2012 Oct 27.
Published in final edited form as: Neuroscience. 2011 Jun 22;194:282–290. doi: 10.1016/j.neuroscience.2011.06.047

Figure 1.

Figure 1

A. Effects of chronic restraint stress on body weight in WT (US, n=22; CS, n=18) and Fmr1 KO (US, n=21; CS, n=20) mice. Each point represents the mean ± SEM for each day of stress. Data were analyzed by means of RM ANOVA with genotype (WT, KO), treatment (US, CS) and day of stress as factors with RM on day of stress. The genotype × treatment × day of stress interaction was statistically significant (F(4.1,316.8) = 2.401, p=0.048). Specific differences between groups at each time point were assessed for statistical significance by means of Bonferroni post-hoc t-tests. Differences between WT-US and KO-US and differences between WT-CS and KO-CS were statistically significant (p<0.05) at all time points. There were no significant differences between WT-US and WT-CS at any time point. Differences between KO-US and KO-CS were statistically significant as indicated on the graph (*, p<0.05).

B. Effects of chronic restraint stress on adrenal gland weight (as a percent of body weight) in WT (US, n=21; CS, n=19) and Fmr1 KO (US, n=20; CS, n=19) mice. Bars are the means ± SEMs. Data were analyzed by means of ANOVA with genotype (WT, KO), treatment (US, CS) as factors. The genotype × treatment interaction was statistically significant (F(1,75) = 5.083, p=0.027). Specific differences between groups were assessed for statistical significance by means of post-hoc Bonferroni t-tests (*, p<0.05; **, p<0.01).