Table 2.
Phthalate Metabolite and BPA Levels in HOME Study Maternal Urinary Samples in Comparison with National Levels
| Metabolite | National Levels Females 2003-04 |
HOME Study 16 week (n=346) |
HOME Study 26 week (n=332) |
|||||
|---|---|---|---|---|---|---|---|---|
| Geomean (95%CI) | Geomean (95%CI) | % > LOD | Geomean (95%CI) | % > LOD | ||||
| MBP/MnBP (ng/mL) | 22.2 | (21.2-23.3) | 24.0 | (21.2-27.1) | 99.7 | 20.3 | (17.9-23.0) | 100 |
| MiBP (ng/mL) | 3.6 | (3.19-3.97) | 4.5 | (4.0-5.2) | 96.0 | 3.6 | (3.1-4.2) | 94.1 |
| DBP sum (nmol/L) | Not | Available | 134 | (119-151) | 99.7 | 113 | (99-128) | 100 |
| MECPP (ng/mL) | 31.9 | (28.1-36.2) | 38.0 | (33.0-43.7) | 100 | 29.9 | (26.1-34.2) | 100 |
| MEHHP (ng/mL) | 19.7 | (17.4-22.2 | 26.9 | (23.0-31.3) | 99.1 | 20.4 | (17.6-23.5) | 99.1 |
| MEOHP (ng/mL) | 13.4 | (11.9-15.1) | 19.9 | (17.1-23.2) | 99.4 | 16.5 | (14.3-19.1) | 98.5 |
| MEHP (ng/mL) | 2.2 | (1.92-242) | 4.9 | (4.2-5.7) | 75.4 | 4.2 | (3.7-4.9) | 77.6 |
| DEHP sum (nmol/L) | Not | Available | 311 | (269-360) | 100 | 245 | (213-281) | 100 |
| BPA (ng/mL) | 2.4 | (2.11-2.75) | 1.8 | (1.6-2.0) | 90 | 1.7 | (1.5-2.0) | 90.3 |
| Creatininea (mg/dL) | 119 | 124 | (84) | 100 | 105 | (75) | 100 | |
*
No National levels available for phthalate metabolite summary measures
a
Mean (std) presented to allow comparison with available normative data (Barr, et al., 2005)