Table 4.

Mulitvariable Models of Associations between Maternal Phthalate and BPA Measures at Two Times and Early Infant Neurobehavior for NNNS Scales with Significant Bivariate Findings at p<.10

NNNS Subscale	Covariates Included	n	Beta	SE	p
			DBP
Arousal – 26w		332	−0.072	0.036	0.04
Higher DBP exposure  associated with lower  (improved) arousal	Log2 creatinine		0.105	0.052	0.04
	Age at exam		0.011	0.008	0.16
	Sex		−0.015	0.078	0.84
	Weight change		−.0002	.0001	0.07
	Drink1		−0.060	0.085	0.48
	Drink2		−0.270	0.113	0.02
	Log2 cotinine max		0.014	0.011	0.18
Regulation – 26w		329	0.080	0.041	0.05
Higher DBP exposure  associated with higher  (improved) self-  regulation	Log2 creatinine		−0.109	0.060	0.07
	Age at exam		−0.001	0.009	0.91
	Sex		−0.144	0.089	0.11
	Weight change		0.0004	0.0002	0.02
	Marital status1		−0.419	0.137	0.002
	Marital status 2		−0.246	0.123	0.05
	Drink1		0.063	0.097	0.52
	Drink2		0.242	0.129	0.06
	High risk status		−0.195	0.132	0.14
Handling - 26w		325	−0.038	0.016	0.02
Higher DBP exposure  associated with less  handling needed	Log2 creatinine		0.049	0.023	0.03
	Age at exam		0.005	0.003	0.12
	Sex		−0.030	0.034	0.39
Movement Quality – 26w		339	0.054	0.029	0.067
Higher DBP exposure  associated with trend of  improved movement  quality	Log2 creatinine		−0.100	0.043	0.02
	Age at exam		0.014	0.006	0.02
	Sex		−0.060	0.063	0.34
	Marital status1		−0.262	0.097	0.008
	Marital status 2		−0.130	0.087	0.14
	High risk status		−0.393	0.095	<.0001
Hypotonia* - 16w		346	0.186	0.114	0.10
	Log2 creatinine		−0.037	0.166	0.82
	Age at exam		−0.035	0.026	0.17
	Sex		−0.109	0.258	0.67
Hypotonia* - 26w		332	0.197	0.122	0.11
	Log2 creatinine		−0.167	0.175	0.35
	Age at exam		−0.36	0.027	0.18
	Sex		0.030	0.264	0.91
			DEHP
Nonoptimal Reflexes **   26w males		158	0.216	0.090	0.02
Higher DBP exposure  associated with more  nonoptimal reflexes	Log2 creatinine		−0.018	0.140	0.90
	Age at exam		−0.011	0.024	0.65
	Income		0.005	0.003	0.14
	Weight change		0.0003	0.0004	0.52
26w females		174	0.019	0.082	0.82
	Log2 creatinine		−0.034	0.143	0.81
	Age at exam		0.016	0.028	0.58
	Income		0.007	0.004	0.05
	Weight change		0.0003	0.0005	0.52
			BPA
Hypotonia* - 16w		346	0.179	0.104	0.09
Higher BPA exposure  associated with trend of  more hypotonia  (reduced tone)	Log2 creatinine		0.067	0.153	0.66
	Age at exam		−0.038	0.026	0.14
	Sex		−0.118	0.261	0.65
	Black race		−0.341	0.310	027

^*Logistic regression applied. Manuscript text reports odds ratio.

^**Sex by phthalate interaction p-values: non-optimal reflexes and DEHP at 26 weeks p=0.04