Table 3.
Summary Statistics and Variance Components Estimates of Genetic and Environmental Effects for Unadjusted Day of Testing Measures of DHEAS Adjusted for Age
| Test Day | Mean DHEAS Levels in ng/ml (SD) |
Mean Time of DHEAS Collection (SD) |
rMZ | 95% CI | rDZ | 95% CI | A | 95% CI | C | 95% CI | E |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Awake | 6.39 (0.05) | 0589h (0.78) | 0.38 | (0.24; 0.50) | 0.26 | (0.09; 0.40) | 0.24 | (−0.13; 0.62) | 0.14 | (−0.19; 0.43) | 0.62 |
| Awake+30 | 5.54 (0.05) | 0644h (0.87) | 0.39 | (0.27; 0.50) | 0.27 | (0.14; 0.40) | 0.23 | (−0.10; 0.58) | 0.16 | (−0.14; 0.43) | 0.61 |
| 10 AM | 5.37 (0.05) | 0973h (0.58) | 0.35 | (0.22; 0.46) | 0.16 | (0.03; 0.30) | 0.37 | (0.02; 0.73) | −0.03 | (−0.32; 0.27) | 0.65 |
| 3 PM | 5.37 (0.05) | 1493h (0.98) | 0.39 | (0.27; 0.51) | 0.20 | (0.08; 0.34) | 0.38 | (0.02; 0.72) | 0.01 | (−0.26; 0.31) | 0.61 |
| Bedtime | 5.25 (0.05) | 2058h (4.67) | 0.32 | (0.15; 0.45) | 0.16 | (0.02; 0.32) | 0.31 | (−0.05; 0.69) | 0.01 | (−0.30; 0.31) | 0.68 |
| Test Overall | 5.59 (0.04) | 0.45 | (0.33; 0.55) | 0.26 | (0.13; 0.38) | 0.38 | (0.05; 0.69) | 0.07 | (−0.19; 0.33) | 0.55 |
rMZ = Monozygotic twin correlation; rDZ = Dizygotic twin correlation
A = Estimate of broad sense heritability, 2(rMZ - rDZ)
C = Estimate of shared environmental effects, 2*rMZ - rDZ
E = Estimate of unique environmental effects 1 – rMZ