Figure 3. Leptin action via LHA LepRbNts neurons regulates body weight and adiposity via.
(A) Body weight, (B) gonadal fat pad weight, (C) percentage fat mass, and (D) percentage lean mass of male Control and Nts-LepRbKO (KO) mice (12–14 wk old, n=23–25 per genotype). (E) ELISA analysis of terminal serum for leptin (13–15 wk old, KO n=15, control n = 16). (F) Weekly food intake from 4–5 wk of age. (n=25 per genotype). Graphed data represent average values ± SEM. *p<0.05 by Student's t test.