Figure 4.

F-D curve of 209-bp 24-unit oligonucleosome chains at 0.15 M monovalent salt with: (a) fast and (b) slow LH binding. Space-filling models based on the same MC stretching simulations. (White and navy) Alternating nucleosomes. (Red) Wrapped DNA. (Turquoise) LH (see Fig. S1). In the curve, different background colors and text describe the different stretching responses that the chromatin fiber exhibits as the pulling force increases, as revealed by the simulation snapshots. (Circled numbers) Relation of each snapshot with a point along the F-D curve.