Table 1. Meiotic analysis of male homozygotes and trivalent-carrying heterozygotes for different Rb fusions.
Rb fusion |
MII |
MI |
||||||||
---|---|---|---|---|---|---|---|---|---|---|
n | n+1 | n+2 | NDJ% | XY | X/Y | A/A | Total | X/Y% | ||
Homozygotes | 6.72 | 52 | 0 | 0 | 0 | 67 | 0 | 0 | 67 | 0 |
6.72 | 22 | 0 | 0 | 0 | 90 | 3 | 0 | 93 | 3.2 | |
6.72 | 61 | 0 | 0 | 0 | 49 | 1 | 0 | 50 | 2.0 | |
7.152 | 53 | 0 | 0 | 0 | 52 | 11 | 0 | 63 | 17.5 | |
7.152 | 47 | 0 | 0 | 0 | 37 | 0 | 0 | 37 | 0.0 | |
0.02 | 52 | 0 | 0 | 0 | 42 | 0 | 0 | 42 | 0.0 | |
0.02 | 52 | 0 | 0 | 0 | 42 | 0 | 0 | 42 | 0.0 | |
Mean | 0 | 3.2±2.4 | ||||||||
Heterozygotes | 6.7 | 50 | 0 | 0 | 0 | 36 | 0 | 0 | 36 | 0.0 |
6.7 | 49 | 0 | 0 | 0 | 37 | 6 | 0 | 42 | 14.3 | |
6.7 | 65 | 6 | 0 | 15.6 | 53 | 1 | 0 | 54 | 1.9 | |
7.15 | 86 | 1 | 0 | 2.3 | 38 | 1 | 0 | 39 | 2.6 | |
7.15 | 56 | 0 | 0 | 0.0 | 46 | 1 | 0 | 47 | 2.1 | |
7.15 | 61 | 0 | 0 | 0.0 | 56 | 2 | 0 | 58 | 3.4 | |
Mean | 3.0±1.1 | 4.0±2.1 | ||||||||
9.12 | 49 | 1 | 0 | 3.9 | ||||||
7.15/9.12 | 46 | 0 | 1 | 8.0 |
Haploid chromosome arm complement is indicated by the number of cells with n, n+1, n+2. Aneuploidy rates (NDJ%) are estimated from metaphase II plates (MII), and sex chromosome (X/Y%) as well as autosome pair (A/A) dissociation from metaphase I plates (MI). XY records the number of cells with paired sex chromosomes. Mean values are provided with standard error.