Table 3.
Wax, Glyceride, and Cholesterol Ester Composition of Human Meibum
| Author/Study | Steroyl:Wax Ester Molar Ratio | Triglyceride:Wax Ester Molar Ratio | Number of Donors Sampled |
|---|---|---|---|
| Cory et al.7 | Not measured | 0.03 (TG:wax and SE) | 7 |
| Mathers et al.47 | 0.61 | 0.37 | 22 |
| Nicolaides et al.5 | 0.86 | 0.11 | 76 pooled |
| McCulley and Shine48 | 0.23 | 0.09 | ? |
| Tiffany13 | 0.78 (range, 0.38–1.2) | 0.87 | 4 |
| Robosky et al.28 | 0.54 | 0.073 | 1 |
| Shine et al.49 | Not measured | ||
| SBBL | 0.082 | 2 | |
| AR | 1 | 0.077 | 2 |
| AR-MKC | 0.157 | 6 | |
| Literature average | 0.60 | 0.13 w/o 0.87 | |
| This study human normal | 0.57 ± 0.09 | 0.19 ± 0.04 | 27 |
| Median | 0.50 | ||
| This study human child (<13 years old) | 0.24 ± 0.08 | 0.17 ± 0.01 | 14 |
| Median | 0.23 | ||
| This study human MGD | 0.34 ± 0.04 | 0.19 ± 0.02 | 48 |
| Median | 0.21 |
SBBL, seborrheic blepharitis; AR, acne rosacea; AR-MKC, AR with meibomian keratoconjunctivitis; MGD, meibomian gland dysfunction.