Table 4.
Laboratorial data
| Variable | Reference | Before Daptomycin | After Daptomycin | P-value |
|---|---|---|---|---|
| Fibrinogen (mg/dl) | 170-400 | 674 ± 109 | 603 ± 125 | 0.03 |
| Hemoglobin (g/dl) | 11.5-15.0 | 10.4 ± 1.6 | 9.4 ± 1.3 | 0.008 |
| Hematocrit (%) | 35-46 | 32 ± 4.8 | 29 ± 3.1 | 0.005 |
| Thrombocyte (x 103/μl) | 150-350 | 392 ± 164 | 334 ± 94 | 0.21 |
| WBC (x 103/μl) | 4.0-11.0 | 12 ± 4.2 | 9 ± 3.2 | 0.001 |
| Creatinine (mg/dl) | 0.55-1.02 | 1.17 ± 0.58 | 1.12 ± 0.53 | 0.69 |
| Total Bilirubin (mg/dl) | ≤ 1.2 | 0.44 ± 0.21 | 0.40 ± 0.25 | 0.53 |
| SGOT (U/I) | ≤ 31 | 23 ± 16 | 32 ± 46 | 0.21 |
| GPT (U/I) | ≤ 34 | 23 ± 13 | 50 ± 92 | 0.24 |
| GGT (U/I) | ≤ 38 | 88 ± 61 | 94 ± 108 | 0.77 |
| CPK (U/I) | ≤ 170 | 51 ± 37 | 50 ± 44 | 0.92 |
| CK-MB (U/I) | ≤ 17 | 23 ± 29 | 14 ± 7 | 0.19 |
| CRP (mg/l) | ≤ 8.0 | 118 ± 72 | 35 ± 32 | 0.0001 |
| LDH | ≤ 232 | 246 ± 71 | 212 ± 55 | 0.05 |
WBC: white blood cell count
SGOT: serum glutamic oxaloacetic transaminase,
SGPT: serum glutamic pyruvic transaminase
GGT: Gamma-glutamyltransferase
CPK: creatine phosphokinase
CK-MB: creatine phosphokinase-MB
CRP: C-reactive protein
LDH: Lactate dehydrogenase