Table 2. Levelsa of miRNA and miRNA* showing dysregulation in (i) miRNA∶miRNA* ratios in metastatic and non-metastatic xenografts and (ii) the levels of miRNA or miRNA* in the two xenograft lines.
Expression level | |||
miRNA | metastatic | non-metastatic | fold change |
miR-7 | 72.35 | 22.5 | 3.22 |
miR-7-1* | 2.76 | 24.54 | −8.88 |
miR-126 | 26005.24 | 1799.7 | 14.45 |
miR-126* | 1099.03 | 3798.06 | −3.46 |
miR-144 | 915.16 | 134.98 | 6.78 |
miR-144* | 5429.24 | 418.37 | 12.98 |
miR-335 | 22.58 | 54.63 | −2.42 |
miR-335* | 65.9 | 91.74 | 1.39 |
miR-374a | 1638.17 | 674.3 | 2.43 |
miR-374a* | 954.79 | 825.93 | 1.16 |
miR-28-3p | 317.5 | 188.15 | 1.69 |
miR-28-5p | 184.78 | 1264.17 | −6.84 |
miR-339-3p | 65.43 | 102.55 | −1.57 |
miR-339-5p | 35.94 | 189.03 | −5.26 |
miR-542-3p | 100 | 26.88 | 3.72 |
miR-542-5p | 0.92 | 12.27 | −13.31 |
Tag counts were normalized to the total counts of sequences that matched the miRBase 15 stem-loop sequences and are expressed as number per 1,000,000 tags.