Table 5. miRNAs down-regulated in the metastatic library§.
references | ||||||
prostate cancer | metastasis in | |||||
miRNA | metastatic | non-metastatic | fold change | prostate cancer | other types of cancer | |
miR-7-1* | 2.76 | 24.54 | −8.88 | |||
miR-15b | 489.84 | 2660.69 | −5.43 | [28] # | ||
miR-16 | 999.03 | 17741.34 | −17.76 | [23]–[25], [38] # | [25] | |
miR-24 | 1046.96 | 8903.54 | −8.50 | [26]–[28], [76] # | [61] | |
miR-24-2*† | 5.07 | 22.50 | −4.44 | |||
miR-26b | 1964.89 | 8991.18 | −4.58 | [28] # | ||
miR-28-5p | 184.78 | 1264.17 | −6.84 | |||
miR-29a | 446.06 | 13028.23 | −29.21 | [26], [28], [29] | ||
miR-29c | 299.99 | 1643.68 | −5.48 | |||
miR-33b | 22.12 | 62.81 | −2.84 | |||
miR-34a | 76.03 | 194.87 | −2.56 | [77], [26] # | [33] | [78] |
miR-95 | 57.60 | 1128.90 | −19.60 | [26] # | ||
miR-101*† | 4.61 | 105.76 | −22.95 | |||
miR-106b | 906.41 | 6545.23 | −7.22 | [30] # | ||
miR-126* | 1099.03 | 3798.06 | −3.46 | [28] # | [34] | |
miR-145 | 103.68 | 297.71 | −2.87 | [23], [24], [27], [29], [30] | [35] | [61] |
miR-146b-5p | 1335.88 | 2765.57 | −2.07 | [26] # | [79], [61] # | |
miR-185 | 84.79 | 448.76 | −5.29 | [60] | ||
miR-186 | 1666.28 | 5838.21 | −3.50 | [61] # | ||
miR-188-5p | 0.92 | 9.64 | −10.46 | |||
miR-191 | 1822.50 | 12911.66 | −7.08 | [26] # | ||
miR-193a-3p | 35.94 | 196.91 | −5.48 | |||
miR-195 | 116.58 | 560.65 | −4.81 | [23], [26] # | ||
miR-196a | 33.64 | 70.99 | −2.11 | [26] # | ||
miR-200b* | 146.54 | 499.30 | −3.41 | |||
miR-200c* | 12.44 | 54.34 | −4.37 | |||
miR-203 | 147.92 | 434.73 | −2.94 | [26] # | [61] | |
miR-203‡ | 224.41 | 334.81 | −1.49 | [26] # | ||
miR-205 | 0.00 | 31.26 | N/A | [24], [31], [32] | [36] |
most abundant miRNA started one base upstream from the mature form of miRBase.
most abundant miRNA started one base downstream from the mature form of miRBase.
Differential expressions all had a >2-fold change and a p<0.001 and are considered statistically significant.
Results from the literature that do not match the down- or up-regulation found in the present study.