Table 7. miRNAs up-regulated in the metastatic library§.
| references | ||||||
| prostate cancer | metastasis in | |||||
| miRNA | metastatic | non-metastatic | fold change | prostate cancer | other types of cancer | |
| let-7d | 671.86 | 322.84 | 2.08 | [26] | ||
| let-7g | 8690.38 | 3448.64 | 2.52 | [23] # | ||
| let-7g* | 42.39 | 3.21 | 13.19 | |||
| let-7i | 851.11 | 400.55 | 2.12 | [26] | [61] | |
| miR-7 | 72.35 | 22.50 | 3.22 | |||
| miR-9 | 20121.64 | 1386.00 | 14.52 | [65],[61] # | ||
| miR-9*‡ | 352.98 | 35.64 | 9.90 | |||
| miR-17 | 12228.92 | 5600.39 | 2.18 | |||
| miR-18a | 1023.45 | 142.57 | 7.18 | |||
| miR-18b | 90.78 | 26.59 | 3.41 | |||
| miR-20b* | 89.40 | 7.60 | 11.77 | |||
| miR-27a | 1568.59 | 721.34 | 2.17 | [26], [28] # | ||
| miR-27b | 1406.39 | 425.38 | 3.31 | [28] # | ||
| miR-30a | 30144.22 | 10956.83 | 2.75 | [61] # | ||
| miR-30a* | 1300.40 | 532.90 | 2.44 | |||
| miR-31 | 80.64 | 3.80 | 21.23 | [30], [24] # | [67], [81] | |
| miR-34c-5p | 2190.22 | 51.13 | 42.84 | |||
| miR-99a | 1017.92 | 330.43 | 3.08 | [23] # | ||
| miR-106a | 2790.65 | 845.51 | 3.30 | [26],[28] [38] # | ||
| miR-125b | 1699.46 | 287.19 | 5.92 | [38]–[40], [23], [24], [27], [29] # | [61] | |
| miR-125b-2* | 15.67 | 1.46 | 10.73 | [57] | ||
| miR-126 | 26005.24 | 1799.70 | 14.45 | [54] # | ||
| miR-128 | 81.10 | 15.48 | 5.24 | [26] # | ||
| miR-136 | 40.55 | 7.89 | 5.14 | |||
| miR-138 | 38.25 | 1.46 | 26.18 | |||
| miR-140-5p | 2458.87 | 723.97 | 3.40 | |||
| miR-142-5p | 104.60 | 26.00 | 4.02 | [61] | ||
| miR-144 | 915.16 | 134.98 | 6.78 | |||
| miR-144* | 5429.24 | 418.37 | 12.98 | |||
| miR-148b*† | 258.97 | 111.31 | 2.33 | |||
| miR-151-3p | 4377.22 | 1866.89 | 2.34 | [66] | ||
| miR-152 | 2662.55 | 582.56 | 4.57 | [28] # | ||
| miR-181a-2* | 19.81 | 0.88 | 22.61 | |||
| miR-200a | 7217.64 | 1066.09 | 6.77 | [58] # | ||
| miR-210 | 16686.78 | 347.38 | 48.04 | [23] | ||
| miR-218 | 140.55 | 70.12 | 2.00 | [25],[26] # | ||
| miR-223* | 16.13 | 0.29 | 55.20 | |||
| miR-301a | 60.83 | 21.62 | 2.81 | [37] | ||
| miR-340* | 46.08 | 16.36 | 2.82 | |||
| miR-374a | 1638.17 | 674.30 | 2.43 | |||
| miR-379 | 104.14 | 35.94 | 2.90 | |||
| miR-449a | 18.43 | 1.17 | 15.77 | [59] # | ||
| miR-450a | 191.24 | 24.83 | 7.70 | [61] | ||
| miR-451 | 4504.40 | 2197.62 | 2.05 | |||
| miR-486-3p | 9.22 | 0.88 | 10.52 | |||
| miR-486-5p | 430.86 | 54.93 | 7.84 | |||
| miR-542-3p | 100.00 | 26.88 | 3.72 | |||
| miR-744* | 17.05 | 3.80 | 4.49 | |||
| miR-1246‡ | 95.39 | 22.50 | 4.24 | |||
†
most abundant miRNA started one base upstream from the mature form of miRBase.
‡
most abundant miRNA started one base downstream from the mature form of miRBase.
§
Differential expressions all had a >2-fold change and a p<0.001 and are considered statistically significant.
#
Results from the literature that do not match the down- or up-regulation found in the present study.