Table 3. Global gene P values for significant associations between common genetic variations in TGF-β signaling pathway and ovarian cancer risk.
| Gene name | Number of SNPs genotyped per gene | P for SNPs in gene, by model | |
| Dominant model | Additive model | ||
| SMAD6 | 29 | .034 | .064 |
| TGFB1 | 6 | .045 | .190 |
| SMAD7 | 21 | .074 | .147 |
| INHBC | 5 | .125 | .137 |
| AMHR2 | 1 | .188 | .130 |
| INHA | 4 | .208 | .640 |
| ACVR2A | 3 | .220 | .184 |
| SMAD2 | 8 | .223 | .264 |
| SMAD3 | 49 | .252 | .779 |
| SMAD1 | 8 | .262 | .050 |
| ACVR2B | 3 | .374 | .465 |
| SMAD9 | 17 | .397 | .307 |
| BMP2 | 14 | .415 | .528 |
| ACVR1B | 3 | .481 | .743 |
| BMP4 | 5 | .570 | .724 |
| NODAL | 6 | .580 | .558 |
| SMAD5 | 5 | .644 | .621 |
| SMAD4 | 4 | .810 | .894 |
| GDF1 | 3 | .893 | .962 |
| BMP1 | 17 | .928 | .948 |
| ACVR1C | 3 | .933 | .878 |
Note: Significant P values in boldface.