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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Breast Cancer Res Treat. 2011 May 20;130(1):273–279. doi: 10.1007/s10549-011-1582-3

Table 3.

Odds ratios (and 95% confidence intervals) for breast cancer by category of maternal weight gain in pregnancy, according to age at diagnosis and ER status of the tumor

Maternal weight gain in pregnancy Age at diagnosis
ER status of tumor
Cases <50 years Cases ≥ 50 years ER+ Cases ER- Cases
Wt gain <10 lbs 19/69 0.95 (0.59–1.54) 9/69 0.93 (0.46–1.89) 15/69 0.95(0.55–1.63) 8/69 1.23 (0.57–2.63)
Wt gain 10–14 lbs 54/222 0.93 (0.69–1.27) 45/222 1.22 (0.83–1.80) 56/222 1.13 (0.82–1.56) 20/222 1.06 (0.62–1.79)
Wt gain 15–19 lbs 113/322 1.05 (0.83–1.34) 47/324 1.09 (0.75–1.61) 83/322 1.08 (0.81–1.43) 30/324 0.95 (0.60–1.51)
Wt gain 20–29 lbs 173/514 1.00 (ref) 64/514 1.00 (ref) 120/514 1.00 (ref) 50/514 1.00 (ref)
Wt gain 30–40 lbs 78/207 1.11 (0.85–1.45) 34/207 1.22 (0.80–1.86) 54/207 1.11(0.80–1.53) 29/207 1.54 (0.97–2.45)
Wt gain 40+ lbs 21/79 0.90 (0.57–1.42) 6/79 0.65 (0.28–1.49) 19/79 1.09 (0.66–1.78) 4/79 0.59 (0.21–1.65)
p-trend* 0.69 0.56 0.99 0.56

Odds ratios are adjusted for birth year of nurse, cohort, family history of breast cancer in nurses' mother or sister (yes/no; as reported by nurse), maternal smoking during pregnancy (no, yes <25 cigs/day, yes >=25 cigs/day).

*

p-trend from model using the midpoint of each weight gain category as a continuous variable.