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. 2011 Feb 22;53(10):749–762. doi: 10.1007/s00234-011-0845-3

Table 8.

The ROI data and results of the corresponding statistical test for the mean diffusivity (MD) values

ROI Subjects p value
AD MCI CN AD–MCI AD–CN MCI–CN
Superior temporal gyrus, ROI1, X ±58, Y −6, z −4 Rt gm 1.045±0.156 0.875±0.072 0.908±0.084 0.00026 0.00490 0.22578
Rt neg 1.049±0.161 0.870±0.076 0.907±0.091 0.00022 0.00500 0.21123
Rt pos 1.042±0.153 0.879±0.069 0.909±0.079 0.00030 0.00450 0.24897
Lt gm 1.023±0.155 0.911±0.117 0.955±0.099 0.02489 0.15434 0.25234
Lt neg 1.027±0.163 0.917±0.127 0.960±0.108 0.03755 0.18508 0.30315
Lt pos 1.022±0.150 0.907±0.110 0.954±0.092 0.01635 0.13488 0.19277
Limbic parahippocampal gyrus, ROI 2, X ±32, y −24, z −22 Rt gm 0.100±0.111 0.891±0.071 0.882±0.060 0.00187 0.00091 0.69383
Rt neg 0.933±0.111 0.877±0.074 0.875±0.061 0.00112 0.00088 0.93385
Rt pos 1.007±0.111 0.906±0.074 0.890±0.058 0.00395 0.00088 0.49030
Lt gm 1.036±0.116 0.879±0.060 0.882±0.075 0.00002 0.00012 0.92913
Lt neg 1.031±0.111 0.868±0.058 0.870±0.074 0.00001 0.00005 0.94042
Lt pos 1.036±0.118 0.890±0.062 0.893±0.078 0.00008 0.00039 0.90633
Middle temporal gyrus, ROI 3, X ±40, y −74, z 28 Rt gm 0.963±0.099 0.837±0.062 0.832±0.058 0.00011 0.00009 0.78235
Rt neg 0.963±0.108 0.832±0.062 0.836±0.062 0.00013 0.00034 0.89277
Rt pos 0.966±0.105 0.843±0.064 0.829±0.054 0.00025 0.00008 0.49316
Lt gm 0.944±0.115 0.852±0.059 0.875±0.078 0.00590 0.05985 0.33837
Lt neg 0.944±0.118 0.846±0.065 0.871±0.077 0.00511 0.05068 0.30961
Lt pos 0.947±0.114 0.859±0.054 0.879±0.081 0.01048 0.14942 0.23174
Occipital cuneus, ROI 4, X ±26, y −84, z 16 Rt gm 0.948±0.090 0.829±0.051 0.839±0.058 0.00004 0.00035 0.61712
Rt neg 0.934±0.082 0.828±0.059 0.839±0.060 0.00015 0.00085 0.59032
Rt pos 0.962±0.106 0.830±0.046 0.838±0.057 0.00004 0.00031 0.65473
Lt gm 0.924±0.103 0.853±0.080 0.879±0.063 0.03507 0.15081 0.31487
Lt neg 0.920±0.104 0.853±0.087 0.873±0.063 0.05182 0.13221 0.45565
Lt pos 0.927±0.107 0.853±0.075 0.884±0.064 0.02715 0.18312 0.21208
Limbic uncus, ROI 5, X ±24, y −4, z −32 Rt gm 1.047±0.142 0.950±0.103 0.928±0.066 0.03111 0.00532 0.46841
Rt neg 1.040±0.165 0.933±0.111 0.918±0.081 0.03475 0.01353 0.65553
Rt pos 1.053±0.135 0.967±0.100 0.943±0.065 0.04522 0.00692 0.42162
Lt gm 1.055±0.118 0.962±0.071 0.912±0.097 0.00053 0.00090 0.61871
Lt neg 1.053±0.119 0.912±0.074 0.899±0.099 0.00023 0.00049 0.66891
Lt pos 1.062±0.124 0.939±0.069 0.923±0.098 0.00118 0.00166 0.57150

Rt right, Lt left, AD Alzheimer's disease, MCI mild cognitive impairment, CN cognitive normal, Gm geometric mean, neg negative, p positive

The ROIs are listed in the table above. The significant level was used with p = 0.016 (p = 0.05/3 times repeated) because we repeated the same tasks three times among the three groups