Table 8.
ROI | Subjects | p value | ||||||
---|---|---|---|---|---|---|---|---|
AD | MCI | CN | AD–MCI | AD–CN | MCI–CN | |||
Superior temporal gyrus, ROI1, X ±58, Y −6, z −4 | Rt | gm | 1.045±0.156 | 0.875±0.072 | 0.908±0.084 | 0.00026 | 0.00490 | 0.22578 |
Rt | neg | 1.049±0.161 | 0.870±0.076 | 0.907±0.091 | 0.00022 | 0.00500 | 0.21123 | |
Rt | pos | 1.042±0.153 | 0.879±0.069 | 0.909±0.079 | 0.00030 | 0.00450 | 0.24897 | |
Lt | gm | 1.023±0.155 | 0.911±0.117 | 0.955±0.099 | 0.02489 | 0.15434 | 0.25234 | |
Lt | neg | 1.027±0.163 | 0.917±0.127 | 0.960±0.108 | 0.03755 | 0.18508 | 0.30315 | |
Lt | pos | 1.022±0.150 | 0.907±0.110 | 0.954±0.092 | 0.01635 | 0.13488 | 0.19277 | |
Limbic parahippocampal gyrus, ROI 2, X ±32, y −24, z −22 | Rt | gm | 0.100±0.111 | 0.891±0.071 | 0.882±0.060 | 0.00187 | 0.00091 | 0.69383 |
Rt | neg | 0.933±0.111 | 0.877±0.074 | 0.875±0.061 | 0.00112 | 0.00088 | 0.93385 | |
Rt | pos | 1.007±0.111 | 0.906±0.074 | 0.890±0.058 | 0.00395 | 0.00088 | 0.49030 | |
Lt | gm | 1.036±0.116 | 0.879±0.060 | 0.882±0.075 | 0.00002 | 0.00012 | 0.92913 | |
Lt | neg | 1.031±0.111 | 0.868±0.058 | 0.870±0.074 | 0.00001 | 0.00005 | 0.94042 | |
Lt | pos | 1.036±0.118 | 0.890±0.062 | 0.893±0.078 | 0.00008 | 0.00039 | 0.90633 | |
Middle temporal gyrus, ROI 3, X ±40, y −74, z 28 | Rt | gm | 0.963±0.099 | 0.837±0.062 | 0.832±0.058 | 0.00011 | 0.00009 | 0.78235 |
Rt | neg | 0.963±0.108 | 0.832±0.062 | 0.836±0.062 | 0.00013 | 0.00034 | 0.89277 | |
Rt | pos | 0.966±0.105 | 0.843±0.064 | 0.829±0.054 | 0.00025 | 0.00008 | 0.49316 | |
Lt | gm | 0.944±0.115 | 0.852±0.059 | 0.875±0.078 | 0.00590 | 0.05985 | 0.33837 | |
Lt | neg | 0.944±0.118 | 0.846±0.065 | 0.871±0.077 | 0.00511 | 0.05068 | 0.30961 | |
Lt | pos | 0.947±0.114 | 0.859±0.054 | 0.879±0.081 | 0.01048 | 0.14942 | 0.23174 | |
Occipital cuneus, ROI 4, X ±26, y −84, z 16 | Rt | gm | 0.948±0.090 | 0.829±0.051 | 0.839±0.058 | 0.00004 | 0.00035 | 0.61712 |
Rt | neg | 0.934±0.082 | 0.828±0.059 | 0.839±0.060 | 0.00015 | 0.00085 | 0.59032 | |
Rt | pos | 0.962±0.106 | 0.830±0.046 | 0.838±0.057 | 0.00004 | 0.00031 | 0.65473 | |
Lt | gm | 0.924±0.103 | 0.853±0.080 | 0.879±0.063 | 0.03507 | 0.15081 | 0.31487 | |
Lt | neg | 0.920±0.104 | 0.853±0.087 | 0.873±0.063 | 0.05182 | 0.13221 | 0.45565 | |
Lt | pos | 0.927±0.107 | 0.853±0.075 | 0.884±0.064 | 0.02715 | 0.18312 | 0.21208 | |
Limbic uncus, ROI 5, X ±24, y −4, z −32 | Rt | gm | 1.047±0.142 | 0.950±0.103 | 0.928±0.066 | 0.03111 | 0.00532 | 0.46841 |
Rt | neg | 1.040±0.165 | 0.933±0.111 | 0.918±0.081 | 0.03475 | 0.01353 | 0.65553 | |
Rt | pos | 1.053±0.135 | 0.967±0.100 | 0.943±0.065 | 0.04522 | 0.00692 | 0.42162 | |
Lt | gm | 1.055±0.118 | 0.962±0.071 | 0.912±0.097 | 0.00053 | 0.00090 | 0.61871 | |
Lt | neg | 1.053±0.119 | 0.912±0.074 | 0.899±0.099 | 0.00023 | 0.00049 | 0.66891 | |
Lt | pos | 1.062±0.124 | 0.939±0.069 | 0.923±0.098 | 0.00118 | 0.00166 | 0.57150 |
Rt right, Lt left, AD Alzheimer's disease, MCI mild cognitive impairment, CN cognitive normal, Gm geometric mean, neg negative, p positive
The ROIs are listed in the table above. The significant level was used with p = 0.016 (p = 0.05/3 times repeated) because we repeated the same tasks three times among the three groups