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. Author manuscript; available in PMC: 2012 Oct 4.
Published in final edited form as: J Am Coll Cardiol. 2011 Oct 4;58(15):1600–1607. doi: 10.1016/j.jacc.2011.07.010

Table 2.

Multivariable association between level of renal function and the risk of presentation of coronary heart disease as acute myocardial infarction versus stable exertional angina.

eGFR,* ml/min/1.73m2 Adjusted Odds Ratio (95% Confidence Interval)
Model 1
(eGFR only)
Model 2
(Model 1 + age, gender, race/ethnicity, family history of coronary heart disease, cigarette smoking history, physical activity level)
Model 3
(Model 2 + prior stroke or peripheral arterial disease, diabetes mellitus, hypertension)
Model 4
(Model 3 + systolic blood pressure, body mass index, prior low-density lipoprotein and high-density lipoprotein cholesterol level)
Model 5
(Model 4 + prior use of statins, β-blockers, calcium channel blockers, ACE inhibitors, ARBs, diuretics
90 to 130 Referent Referent Referent Referent Referent
60 to 89 1.25 (0.96–1.63) 1.30 (0.98–1.73) 1.33 (1.00–1.78) 1.31 (0.98–1.80) 1.36 (1.00–1.86)
45 to 59 1.27 (0.81–1.97) 1.38 (0.86–2.21) 1.34 (0.84–2.16) 1.34 (0.82–2.19) 1.55 (0.91–2.62)
<45 2.58 (1.16–5.75) 2.77 (1.21–6.34) 2.64 (1.15–6.10) 2.71 (1.16–6.34) 3.82 (1.55–9.46)
*

eGFR= estimated glomerular filtration rate

ACE = angiotensin-converting enzyme

ARB = angiotensin II-receptor blockers