Table 2.
eGFR,* ml/min/1.73m2 | Adjusted Odds Ratio (95% Confidence Interval) | ||||
---|---|---|---|---|---|
Model 1 (eGFR only) |
Model 2 (Model 1 + age, gender, race/ethnicity, family history of coronary heart disease, cigarette smoking history, physical activity level) |
Model 3 (Model 2 + prior stroke or peripheral arterial disease, diabetes mellitus, hypertension) |
Model 4 (Model 3 + systolic blood pressure, body mass index, prior low-density lipoprotein and high-density lipoprotein cholesterol level) |
Model 5 (Model 4 + prior use of statins, β-blockers, calcium channel blockers, ACE† inhibitors, ARBs,‡ diuretics |
|
90 to 130 | Referent | Referent | Referent | Referent | Referent |
60 to 89 | 1.25 (0.96–1.63) | 1.30 (0.98–1.73) | 1.33 (1.00–1.78) | 1.31 (0.98–1.80) | 1.36 (1.00–1.86) |
45 to 59 | 1.27 (0.81–1.97) | 1.38 (0.86–2.21) | 1.34 (0.84–2.16) | 1.34 (0.82–2.19) | 1.55 (0.91–2.62) |
<45 | 2.58 (1.16–5.75) | 2.77 (1.21–6.34) | 2.64 (1.15–6.10) | 2.71 (1.16–6.34) | 3.82 (1.55–9.46) |
eGFR= estimated glomerular filtration rate
ACE = angiotensin-converting enzyme
ARB = angiotensin II-receptor blockers