Figure 16.

GMABM response to phosphate depletion alone. Selected frames from the model interface taken at 6, 12, 24 and 48 hrs of simulated time during simulation of phosphate depletion in the integrated GMABM. Pseudomonas agents are red pentagons and intact tight junctions are seen as the purple background, with black background indicating severe barrier disruption. Phosphate depletion alone yielded moderate to severe barrier disruption after 48 hours. This response was more severe than expected given prior experimental referent data.