Table 4.
Propensity score analysis results 2: Survival impact across quintiles based on the propensity to receive aggressive-approach chemotherapy within 14 days of death among chemotherapy recipients with metastatic non-small cell lung cancer, who survived at least 3 months after their cancer diagnosis (n = 3,534)
| Analysis | Variables | HR | (95%CI) | P-value |
|---|---|---|---|---|
| Stratified analysis | ||||
| Lowest quintile of PS* | Standard chemotherapy | 1.00 | - | - |
| Aggressive-approach chemotherapy | 1.32 | (0.90, 1.92) | 0.15 | |
| Second quintile of PS | Standard chemotherapy | 1.00 | - | - |
| Aggressive-approach chemotherapy | 1.30 | (0.98, 1.72) | 0.07 | |
| Third quintile of PS | Standard chemotherapy | 1.00 | - | - |
| Aggressive-approach chemotherapy | 1.22 | (0.81, 1.84) | 0.35 | |
| Fourth quintile of PS | Standard chemotherapy | 1.00 | - | - |
| Aggressive-approach chemotherapy | 1.21 | (0.94, 1.56) | 0.14 | |
| Highest quintile of PS† | Standard chemotherapy | 1.00 | - | - |
| Aggressive-approach chemotherapy | 0.85 | (0.68, 1.07) | 0.16 | |
| Multiple Cox regression adjustment using the PS | Standard chemotherapy | 1.00 | - | - |
| Aggressive-approach chemotherapy | 1.21 | (1.00, 1.48) | 0.05 |
Abbreviation: HR, hazard ratio; CI, confidence interval; PS, propensity score.
* Patients are least likely to receive "aggressive-approach chemotherapy within 14 days of death."
† Patients are most likely to receive "aggressive-approach chemotherapy within 14 days of death."