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. 2011 Jul 6;85(4):858–866. doi: 10.1095/biolreprod.111.092072

FIG. 6.

FIG. 6.

Inhibition of gelatinolytic activity increases hepsin in Ovcar-3 cell conditioned media. Graphical representation of Western blot analysis results of the 29-kDa fragment of hepsin in Skov-3, Caov-3, and Ovcar-3 cells treated with either DMSO (control) or 100 μM of MMP2/9 inhibitor (inhibitor) for 24 h. The 29-kDa fragment was significantly increased in the conditioned media of Ovcar-3 cells treated with MMP2/9 inhibitor compared to Ovcar-3 cells treated with vehicle (*); n = 4 separate, independent experiments, and all the values were normalized to actin in each sample.