Table 3.
Measurement properties of the predictive models for the individual and combined (QDA) miRNAs confirmed by RT-qPCR using the ΔCt data obtained in tissue samples. IF/TA was defined as positive.
Specificity | Sensitivity | PPV | NPV | ACC | TP | TN | FP | FP | AUC | |
---|---|---|---|---|---|---|---|---|---|---|
miR-142- 3p |
1.00 | 0.89 | 1.00 | 0.80 | 0.93 | 17 | 8 | 0 | 2 | 0.974 |
miR-32 | 0.88 | 0.89 | 0.94 | 0.78 | 0.89 | 17 | 7 | 1 | 2 | 0.822 |
miR-204 | 1.00 | 0.95 | 1.00 | 0.89 | 0.96 | 18 | 8 | 0 | 1 | 0.967 |
miR-107 | 0.88 | 1.00 | 0.95 | 1.00 | 0.96 | 19 | 7 | 1 | 0 | 0.954 |
miR-211 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 19 | 8 | 0 | 0 | 1.000 |
QDA | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 19 | 8 | 0 | 0 | 1.00 |
PPV: positive predictive value; NPV: negative predictive value; ACC: accuracy; TP: true positive; TN: true negative; FP: false positive; FN: false negative; AUC: area under the curve.
QDA = Quadratic Discriminant Analysis