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. 2011 Sep 14;31(37):13057–13067. doi: 10.1523/JNEUROSCI.3248-11.2011

Figure 4.

Figure 4.

The effect of Wnt1 in the amygdala on fear learning and memory. a, b, Cresyl violet staining of parallel sections showing the absence of damage in vehicle- (a) or Wnt1- (b) infected regions. c, Activity measures of mice receiving injections of vehicle or Wnt1 and placed in an open-field apparatus for 10 min. n = 13 for vehicle, n = 15 for Wnt1. d, Acquisition curve showing percentage time spent freezing during each tone before footshock presentation. n = 15 for vehicle, n = 23 for Wnt1. e, f, Animals were injected with either vehicle or Wnt1 before training, and vehicle or Wnt1 after training (Pre-training/Post-training). e, Percentage time spent freezing when tested 48 h after fear conditioning, and presented with 15 tone presentations. f, Freezing data from e, presented in three blocks of five tone presentations. White bars are Veh/Veh, gray bars are Veh/Wnt1, and black bars are Wnt1/Veh animals. For both e and f, n = 8 for Veh/Veh, n = 7 for Veh/Wnt1, n = 12 for Wnt1/Veh. Data are mean ± SEM; **p < 0.01, *p < 0.05, ANOVA with post hoc analyses.