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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Expert Rev Clin Pharmacol. 2011 Sep;4(5):643–652. doi: 10.1586/ecp.11.43

Table 1.

Pediatric or infant dosing compared with adult dosing of commonly used antimicrobials.

Drug Preferred
adult dosing
(mg/kg/day)		 Pediatric or
infant dosing
(mg/kg/day)		 Pharmacokinetic data
available in infants
<28 weeks gestation		 Ref.
Ampicillin 30–50 50 None [83]
Ciprofloxacin 10 30 None [84]
Daptomycin 4–6 12 None [85]
Metronidazole 30 15 Limited (>7 days of life) [86]
Fluconazole 3–6 12 Yes [12]
Micafungin 2 10 Yes [14,15,87]