Table 1.
Clinical characteristics of healthy non-pregnant and pregnant women and preeclamptic patients
| Healthy non-pregnant women (n = 59) | Healthy pregnant women (n = 60) | Preeclamptic patients (n = 60) | |
|---|---|---|---|
| Age (years) | 28 (23-35) | 30 (28-32) | 29 (26-32) |
| Pre-pregnancy BMI (kg/m2) | n.a. | 21.0 (19.5-22.6) | 25.5 (21.6-28.1)d |
| BMI at blood draw (kg/m2) | 20.8 (19.6-22.9) | 25.8 (24.3-27.9)b | 29.9 (26.9-33.3)b, d |
| Smokers | 14 (23.7%) | 0 (0%)b | 3 (5.0%)a |
| Primiparas | n.a. | 37 (61.7%) | 38 (63.3%) |
| Systolic blood pressure at blood draw (mmHg) | 115 (110-120) | 110 (107-120) | 162 (155-180)b, d |
| Diastolic blood pressure at blood draw (mmHg) | 80 (70-80) | 70 (60-80)b | 100 (97-110)b, d |
| Gestational age at blood draw (weeks) | n.a. | 36 (36-37) | 37 (36-39) |
| Gestational age at delivery (weeks) | n.a. | 39 (38-40) | 38 (37-39)d |
| Fetal birth weight (grams) | n.a. | 3450 (3150-3700) | 3125 (2450-3475)d |
| Fetal growth restriction | n.a. | 0 (0%) | 11 (18.3%)d |
Data are presented as median (interquartile range) for continuous variables and as number (percentage) for categorical variables
n.a.: not applicable; BMI: body mass index
a p < 0.05 versus healthy non-pregnant women
b p < 0.001 versus healthy non-pregnant women
c p < 0.05 preeclamptic patients versus healthy pregnant women
d p < 0.001 preeclamptic patients versus healthy pregnant women