Figure 6.
Masson’s trichrome stained explanted cross-sections showed minimal cellular infiltration in the electrospun PEUU (A), and extensive cellular infiltration into the biohybrid scaffold (B). A magnified image of electrospun PEUU showed minimal cellular ingress with tissue encapsulation (C). A magnified image emphasizes the cellularity and extracellular matrix deposition, as well as remnant polymer fibers (white) for the biohybrid scaffold (D). Immunohistochemistry of the electrospun scaffold shows surrounding macrophage (red, CD68) and positive smooth muscle actin expression(green) (E), however Immunohistochemistry of the biohybrid explanted material shows macrophage infiltration (red, CD68) and positive smooth muscle actin expression (green) (F).