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. 2011 Oct 3;6(10):e25369. doi: 10.1371/journal.pone.0025369

Figure 1. Quaternary structure in solution.

Figure 1

Left: Size exclusion with MALS detection reveals monomeric Na-SLP-1 and dimeric Ac-SLP-1 at pH 7.5 and 5.0 under normal salt conditions (representative chromatograms shown). Right: Ac-SLP-1 is exclusively observed as a dimer on native gels. The protein migrates at 20 kDa under native conditions (Lane 1), but at smaller sizes in the presence of SDS (Lane 2). The migration behaviour of Na-SLP-1 on native gels does not allow analysis due to smeared bands (data not shown).