Table 1. Anatomic and hemodynamic data in Sham and CHF rats.
Sham | CHF | |
n | 48 | 48 |
Body weight (g) | 358.2±6.7 | 351.7±6.9 |
Heart weight (g) | 1.3±0.1 | 1.5±0.1 * |
Heart weight/body weight (g/kg) | 3.5±0.2 | 4.3±0.2 * |
Infarct size (% LV area) | 0 | 34.0±2.3 * |
Systolic pressure (mm Hg) | 127.0±4.6 | 111.8±4.3 * |
Diastolic pressure (mm Hg) | 75.5±2.9 | 76.1±2.8 |
Mean arterial pressure (MAP, mm Hg) | 94.6±3.9 | 89.4±3.7 |
Heart rate (HR, beats/min) | 376.9±8.1 | 383.3±7.2 |
LV systolic pressure (LVSP, mm Hg) | 134.5±4.0 | 114.6±4.9 * |
LV end-diastolic pressure (LVEDP, mm Hg) | 0.3±0.9 | 15.0±0.9 * |
+LV dP/dtmax (mm Hg/sec) | 3510.5±106.7 | 1930.8±89.3 * |
LV, left ventricle; +LV dP/dtmax, maximum of the first differentiation of left ventricular pressure. Values are mean ± SE.
*P<0.05 compared with Sham rats.