Figure 6. Different smoke exposure paradigms result in different GSH levels.

Mice were exposed to acute 2 h cigarette smoke (CS) exposure with little rest before sampling of the ELF and BAL cell GSH which resulted in depleted GSH levels. However, after a 24 h exposure which includes a rest period there is a full adaptive response with elevated ELF and BAL cell GSH levels. Data represented as mean ± SEM, with *p<0.05, ***p<0.001 compared to either ELF or BAL cell control.