Descending modulatory pathways. Bars indicate 100μm.
A) Serotonergic fibers in the DL were more densely distributed with significant difference in NBQX&NRP/GRP rats compared to NRP/GRP alone or OP-Controls, which close to unoperated normal controls
B) In NRP/GRP recipients, but not Unoperated Controls or OP-Controls, 5-HT fibers were identified in the LF adjacent to the DL nucleus, which was much denser in rats with combined treatment of NRP/GRP and NBQX.
C) In the DH, 5-HT-positive fibers in the DH were much denser in NBQX&NRP/GRP rats compared to NRP/GRP alone or OP-Controls (arrow).