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. Author manuscript; available in PMC: 2012 Oct 3.
Published in final edited form as: Mol Pharm. 2011 Aug 15;8(5):1619–1628. doi: 10.1021/mp200092v

Table 2. Number and chemical diversity of small drug-like molecules with reported subcellular localization(s).

Chemical structures and reference articles can be found in the supporting information.

Localization Number of
compounds
% Number of references
Total 967 100 448
      Endo-lysosomes 226 23 96
      Mitochondria 259 27 136
      Nucleus 123 13 67
      Plasma membrane 162 17 75
      Endoplasmic reticulum
      & Golgi apparatus
37 4 26
      Cytosol 59 6 36
      Multiple sites 101 10 71