Table 2. Number and chemical diversity of small drug-like molecules with reported subcellular localization(s).
Localization | Number of compounds |
% | Number of references |
---|---|---|---|
Total | 967 | 100 | 448 |
Endo-lysosomes | 226 | 23 | 96 |
Mitochondria | 259 | 27 | 136 |
Nucleus | 123 | 13 | 67 |
Plasma membrane | 162 | 17 | 75 |
Endoplasmic reticulum & Golgi apparatus |
37 | 4 | 26 |
Cytosol | 59 | 6 | 36 |
Multiple sites | 101 | 10 | 71 |