. Author manuscript; available in PMC: 2012 Dec 1.

Published in final edited form as: Neurobiol Dis. 2011 Jul 3;44(3):270–276. doi: 10.1016/j.nbd.2011.06.019

Table 1.

Respiratory control ratio (RCR) Mitochondrial respiratory capacity (MRC) and OXPHOS control ratio (OCR) of brain mitochondria using glutamate+malate (Glu+Mal) or succinate (Succ) as substrates

	Substrate	FVB		Immp2l^+/−
	Substrate	Ctr	5 h	Ctr	5h
RCR	Glu+Mal	5.04±0.66	3.37±0.16**	5.97±0.40	3.19±0.11***
RCR	Succ	3.18±0.07	3.0±0.01	3.48±0.08	2.86±0.07**
MRC	Glu+Mal	1.0±0.05	0.99±0.04	1.18±0.12	0.87±0.02*
MRC	Succ	1.0±0.02	0.79±0.09*	1.17±0.01	0.82±0.10**
OCR	Glu+Mal	0.61±0.03	0.45±0.03**	0.76±0.07	0.51±0.03***
OCR	Succinate	1.0±0.01	0.91±0.01**	1.0±0.02	0.80±0.01***