Typical morphologies of assemblies formed from pure recombinant rP172 and rP148 at pH8.0, in Tris-HCl buffer, at 37 °C. (A) representative uniformly dispersed spherical particles of rP172 (white arrow). Inset shows a typical elongated pearl-like assembly, consisting of assembly particles with ellipsoidal shape. (B) Representative distribution of rP148 spherical particles with some randomly associated aggregates (white arrow), and a small amount of larger aggregates (black arrow), Inset shows the distribution of typical rP148 spherical particles associated to form random morphologies and sizes.