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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: J Struct Biol. 2011 Aug 5;176(2):220–228. doi: 10.1016/j.jsb.2011.07.016

Figure 5.

Figure 5

Proposed mechanism for the assembly of amelogenin hierarchically associated microstructures, formed from co-assembly of rP172 with its cleavage products during in vitro digestion by rpMmp-20. (A) and (B) represent the assembly tendencies of pure rP172 and rP148, respectively, in solution; (C-F) Represent the rP172 co-assembly with its digestion products during the four stages of proteolysis in vitro by rpMmp-20, resulting in the formation of hierarchically associated microstructures. The detailed analysis is described in the text. The scale is arbitrary and does not represent the actual ratios of the morphologies evolved.