Figure 3.

A) Comparisons of activation during pursuit tracking between controls (N=20) and untreated patients with (A.1) schizophrenia (N=24), and (A.2) psychotic bipolar disorder (N=13). Activations in red show regions with higher activations in patients compared to controls. For more detail see Table 3. B) Differences in correlations of V5 activation during motion processing with activation across the brain during pursuit tracking between controls (N=20) and untreated patients with (B.1) schizophrenia (N=24), and (B.2) psychotic bipolar disorder (N=13). Activations in blue show regions with weaker correlations in patients compared to controls. Note, that while activation in anterior intraparietal sulcus (3) was increased in patients relative to controls during pursuit its correlation with activation in visual area V5 during passive motion processing was attenuated in both patient groups implying impaired transfer of visual motion information to parietal association cortex. 1 = dorsomedial thalamus, 2 = dorsolateral prefrontal cortex, 3 = anterior intraparietal sulcus, 4 = posterior superior temporal sulcus. The color bar indicates t-values; for more detail see table 5.