Table 1.

The number of experimentally observed versus predicted transmembrane helices in globular, transmembrane, and prion proteins

Predictions by four different algorithms were made via the Internet by using the corresponding servers for 523 globular proteins, 158 membrane proteins with known transmembrane topology, and six prion proteins. The methods used and proteins selected are given in the text. For each structural class, the number of proteins with a given number of transmembrane helices (TMHs) observed (red) or predicted (blue) is shown.