Table 5.

Values of the cross-validated root-mean-square error RMSECV test

QSAR model for dependent variable	RMSECV test
	Leave-one-out method				Leave-ten-out method
	1a	2	3	4	1	2	3	4
ΔT m	3.36	2.53	2.56	2.39	3.44	2.63	2.64	2.41
ILS	53.39	42.10	28.48	22.79	54.23	42.35	28.74	22.27

^a1–4 represents RMSECV test performed only for one, combined two and three, and for all the four significance descriptors in QSAR models, respectively. In the case of QSAR model, for ΔT _m as dependent-variable values, 1–4 were obtained for only GATS7e, GATS7e combined with μ_i, GATS7e combined with μ_i and H-047, GATS7e combined with μ_i, H-047, and Mp descriptors. In the case of QSAR model for ILS as dependent-variable values, 1–4 were obtained for only G3m, G3m combined with logP, G3m combined with logP and G2p, and G3m combined with logP, G2p and G3p descriptors