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Chromosomal gains and losses involving genes important for GBM progression in newly diagnosed and untreated patients
| Patient | Chromosomal losses | Genes | Chromosomal gains | Genes |
|---|---|---|---|---|
| 2 | 10 | PTEN | 12q, 15p, 21 | MDM2, Gli1 |
| 8 | 9p, 10, 13, 18q | p16, PTEN | 7 (gain and amp) | EGFR |
| 10 | 10 | PTEN | 7 (gain) | EGFR |
| 11 | 10 | PTEN | 7 (gain), 12 (amp) | EGFR, MDM2, Gli1 |
| 20 | 6q, 9p, 10, 14 | p16, PTEN | 7 (gain and amp) | EGFR |
Summary of genetic alterations detected by array CGH involving genes of known relevance to GBM progression
