Table 1.
Characteristics of Patients Hospitalized with Acute Myocardial Infarction (AMI) According to Age and Sex (1986–2005)
| Men |
Women |
|||||||
|---|---|---|---|---|---|---|---|---|
| Characteristics | <65 y (n=2,554) |
65–74y (n=1,545) |
≥75y ( n=1,808) |
P- value |
<65y (n=855) |
65–74y (n=1,092) |
≥75y (n=2,459) |
P- value |
| Age (mean ± SD, years) | 53.4 (±8.0) | 69.7 (±2.9) | 81.8 (±5.1) | 55.2 (±7.6) | 70.0 (±2.8) | 83.3 (±5.7) | ||
| White (%) | 91.9 | 95.0 | 97.6 | <0.001 | 90.0 | 93.2 | 96.4 | <0.001 |
| Marital status (%) | ||||||||
| Single | 14.3 | 9.6 | 7.2 | <0.001 | 11.4 | 10.4 | 10.6 | <0.001 |
| Married | 73.8 | 76.9 | 67.3 | 60.1 | 45.3 | 26.0 | ||
| Divorced | 9.6 | 5.9 | 3.1 | 14.3 | 7.4 | 2.8 | ||
| Widowed | 2.2 | 7.5 | 22.5 | 11.5 | 37.0 | 60.6 | ||
| Medical History (%) | ||||||||
| Atrial fibrillation | 2.7 | 11.2 | 19.7 | <0.001 | 2.4 | 8.8 | 17.5 | <0.001 |
| Hypertension | 48.0 | 59.4 | 64.3 | <0.001 | 56.0 | 69.9 | 72.8 | <0.001 |
| Heart failure | 6.2 | 17.2 | 29.0 | <0.001 | 13.0 | 21.0 | 33.1 | <0.001 |
| Diabetes | 20.9 | 33.4 | 31.0 | <0.001 | 35.8 | 39.8 | 30.0 | <0.001 |
| Stroke | 4.2 | 11.7 | 16.8 | <0.001 | 6.7 | 10.7 | 13.7 | <0.001 |
| AMI characteristics (%) | ||||||||
| Initial | 72.7 | 59.6 | 58.1 | <0.001 | 73.0 | 66.9 | 62.3 | <0.001 |
| Q-wave | 46.1 | 35.9 | 22.8 | <0.001 | 37.2 | 31.5 | 27.1 | <0.001 |
| STEMI* | 53.1 | 43.0 | 26.9 | <0.001 | 47.0 | 34.6 | 30.7 | <0.001 |
| Pre-hospital delay (hours)*, | ||||||||
| median (IQR) | 1.9(1.0– 4.2) | 2.0(1– 4.5) | 2.5(1.2–5.1) | <0.001 | 2.0(1.0–4.7) | 2.4(1.3–5.5) | 2.3(1.2–5.0) | 0.05 |
| Clinical parameters on admission, median (IQR) | ||||||||
| Heart rate(beats/min) | 80(67–94) | 81( 67–100) | 87(71–102) | <0.001 | 83(70–99) | 84(72–102) | 88(74–105) | <0.001 |
| Systolic BP (mmHg) | 141(122–162) | 142(121–160) | 140(117–160) | 0.05 | 142(121–164) | 143(120–170) | 141(120–165) | 0.83 |
| Diastolic BP (mmHg) | 84(70–98) | 80(67–91) | 73(61–86) | <0.001 | 80(64–92) | 77(64–90) | 70(57.5–86) | <0.001 |
| BMI(kg/m2)* | 28.6(25.7–32.3) | 27.3(24.4–30.3) | 25.6(23.1–28.0) | <0.001 | 28.1(24.5–33.1) | 27.3(23.0–32.1) | 24.6(21.3–28.3) | <0.001 |
| Laboratory findings on admission, median (IQR) | ||||||||
| Cholesterol(mg/dl) | 210(171–236) | 186(158–223) | 172(142–205) | <0.001 | 209(174–247) | 215(174–251) | 199(91–235) | <0.001 |
| LDL(mg/dl) | 115(94–142) | 105(82–124) | 97(75–121) | <0.001 | 111(87–142) | 107(84–141) | 102(78–133) | <0.004 |
| Glucose(mg/dl) | 134(112–178) | 151(119–209) | 150(120–209) | <0.001 | 146(116–238) | 163(125–247) | 161(126–228) | 0.02 |
| Creatinine (mg/dl) | 1.1(0.9–1.2) | 1.2(1.0–1.5) | 1.4(1.1–1.9) | <0.001 | 0.9(0.8–1.2) | 1.0(0.9–1.3) | 1.2(0.9–1.6) | <0.001 |
| Length of stay (days), | ||||||||
| median (IQR) | 6(3–9) | 7(4–10.5) | 6(4–10) | <0.001 | 6(4–10) | 7(4–11) | 6(4–10) | <0.001 |
IQR: Inter quartile range; LDL, low-density lipoprotein cholesterol;
*
Information on pre-hospital delay, body mass index (BMI), acute presenting symptoms, and STEMI was recorded beginning in 1991, 1995, and 1997, respectively.