Table 2.

Appendix 1 - RTOG late toxicity scale

RTOG GRADE
	0	I	II	III	IV
Bladder	None	Slight epithelial atrophy; minor telangiectasia (microscopic hematuria)	Moderate frequency; generalized telangiectasia; intermittent macroscopic hematuria	Severe frequency & dysuria; severe telangiectasia; frequent hematuria; reduction in bladder capacity (< 150 cc)	Necrosis/Contracted bladder (capacity < 100 cc); severe hemorrhagic cystitis
Small/Large intestine	None	Mild diarrhea; mild cramping; bowel movement 5 times daily; slight rectal discharge or bleeding	Moderate diarrhea and colic; bowel movement > 5 times daily; excessive rectal mucus or intermittent bleeding	Obstruction or bleeding, requiring surgery	Necrosis/Perforation Fistula