Figure 2.
Response of ovarian cancer cells to docetaxel and carboplatin treatments: SKOV-3 and OVCAR-3 cells exposed to a range of docetaxel (0.1-316 nM) and carboplatin (1-400 μM) concentrations were evaluated for cell viability using WST-1 assay. Data were plotted as the percentage of vehicle control treated cells (polysorbate 80+ethanol and sterile water, for docetaxel and carboplatin, respectively) using GraphPad Prism, version 5. Dose response curves for SKOV-3 and OVCAR-3 cells treated with docetaxel (panel A) or with carboplatin (panel B) for day 5 are shown. Values represent a mean (± SEM) of three experiments. R2 values > 0.9 suggest that data are reliable and fit the statistical considerations. The corresponding IC50 values are also shown.