Table 1.
List of proteins that displayed significantly reduced expression levels in PNP-GDEPT treated samples
| Name of the Protein Identified |
Hit Value (untreated/treated) |
Ratio Transformed log (untreated:treated)1 |
|---|---|---|
| Keratin 5 | 13/0 | 19,306 |
| Keratin 77 | 12/0 | 18,502 |
| Cadherin 6 (K-cadherin) | 7/0 | 14,999 |
| Desmoplakin | 6/0 | 14,037 |
| Plakoglobin | 3/0 | 10,000 |
| Spondin 1 | 3/0 | 10,000 |
| Dynactin 1 | 2/0 | 7,925 |
| Agrin | 2/0 | 7,925 |
| Filaggrin | 2/0 | 7,925 |
| Karyopherin alpha1 | 2/0 | 7,925 |
| Antiquitin (ALDH7A1) | 2/0 | 7,925 |
| Epoxide hydrolase | 2/0 | 7,925 |
| Insulysin | 2/0 | 7,925 |
| BRI3 binding protein (Cervical cancer 1 proto-oncogene-binding protein KG19) |
3/0 | 10,000 |
| Ribosomal protein L4 | 5/0 | 12,924 |
| Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) | 3/0 | 10,000 |
| Mitochondrial trifunctional protein, beta subunit | 3/0 | 10,000 |
| Polymerase (RNA) II (DNA directed) polypeptide E | 3/0 | 10,000 |
| Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 5/0 | 12,924 |
| v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) (RalB) | 2/0 | 7,925 |
1Confidence intervals for estimated mean of population: For 0.95 CI: 232.9632 ± 123.8158; For 0.99 CI: 232.9632 ± 163.636