Table 1.

Genes required for the innate immune response to MCMV infection.

	Gene name	Protein	Evidence [References]
Sensors	Ly49h	Ly49H	QTL [56,57]
	Tlr3	TLR3	KO [9]
	Tlr9	TLR9	ENU [9]
	Il15rb	IL-15R	Blocking Ab [31]
	Ifngr	IFN-γR	KO [109]
	Ifnar	IFN-αR	KO [32]
Extracellular signals	Il12b	IL-12	KO [29,43]
	Il18	IL-18	KO [29,43]
	Infg	IFN-γ	KO [43]
	Mip1a	MIP-1α	KO [110]
Transmitters	Dap12	KARAP/DAP12	KO [61,62]
	Myd88	MyD88	KO [9,11,13]
	Trif	Trif	ENU [8]
	Irf-1	IRF1	KO [109]
	Stat4	STAT4	KO [31]
	Stat1	STAT1	KO [33,34]
	Tyk2	TYK2	KO [35]
Effectors	Pfr1	Perforin	KO [52, 101,102]
	Lyst	Lyst	QTL [111]
	Rab27a	Rab27a	QTL (Georgel P.,
	Unc13d	Unc13d	ENU [82]
	Inos	iNos	KO [109]
Homeostasis	Kcnj8	Kir6.1	ENU? [103]

KO, knock-out, Ab, antibody, QTL, quantitative trait loci, ENU, N-ethyl-N-nitrosourea.