Table 1.

Signaling components of the Epo/EpoR pathway activated by SFFV. SFFV-P and SFFV-A, which have different effects on erythroid cell differentiation, are compared.

Signaling Components of Epo/EpoR Pathway	SFFV-P	SFFV-A	Reference
Shc	+	+	[47]
Grb2	+	+	[47]
Ras	+	+	[47]
Raf-1	+	+	[46]
MEK	+	+	[46]
ERK 1/2	+	+	[46]
JNK	+	+	[48]
Stat1	+	−	[50–52]
Stat3	+	+	[50–52]
Stat5	+	−	[50–52]
PI 3-kinase	+	+	[43]
IRS-2	+	+	[43]
Gab1	+	+	[43]
Gab2	+	+	[43]
PKC	+	+	[47]
Akt	+	+	[43]
SHIP	+	+	[43]