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. 2010 Jul 7;2(7):1427–1447. doi: 10.3390/v2071427

Table 1.

HTLV-1-infected cells polarize their MTOCs to the cell-cell junction in CD4+ T-cell conjugates. Two experiments were performed, each with fresh ex vivo CD4+ T cells from an unrelated HTLV-1-infected subject. Conjugates were allowed to form for 30 min (Subject 1) or 60 min (Subject 2), then were fixed and stained for HTLV-1 Gag p19 and tubulin alpha. Only conjugates containing two cells were counted. The figures denote the number (percentage) of cells whose MTOC was polarized to the cell-to-cell junction. Odds ratio(a) of MTOC polarization in Gag p19+ cells, comparing the number of polarized MTOCs with (polarized + not seen) MTOCs. This table was originally published in the material accompanying reference [32].

MTOC orientation Uninfected control subject HTLV-1-infected subjects
Subject 1 Subject 2
Gag p19 Gag p19+ Gag p19 Gag p19+
Polarized % 79 (18.7) 85 (25.9) 163 (58.2) 45 (22.0) 59 (53.2)
Not polarized % 322 (76.3) 217 (66.2) 111 (39.6) 160 (78.0) 52 (46.8)
Not seen 21 (5) 26 (7.9) 6 (2.1) 0 (0.0) 0 (0.0)
Total 422 (100.0) 328 (100.0) 280 (99.9) 205 (100.0) 111 (100.0)
Odd ratio a (95% confidence interval)
χ2 =(P<<0.001)
3.98 (2.83 – 5.61)
χ2 = 63.9 (P<<0.001)
4.02 (2.45–6.64)
χ2 = 30.4 (P<<0.001)
Subject 1 and subject 2 combined:
4.07 (3.07 – 5.39)
χ2 = 99.0 (P<<0.001)